As is the case with most older Konami hardware, the Twinkle is finicky with replacement CD-ROM devices. If you purchase the wrong one, it may boot but take longer to load and occasionally error out with a SCSI timeout message. This is harmless but annoying.
A TEAC CD-516S 16X SCSI CD-ROM drive has been tested working for several days in Twinkle hardware. A TEAC CD-532S has also been verified to work. When swapping the drives, you will have to disassemble pretty much the entire stack since they placed the nuts holding the drive bay in an awkward position. Make sure the new drive is set to SCSI ID 4 and has TERM and PARITY jumped.